For that you will first have to delete the invoice from GSTN on which IRN was generated and then upload a fresh invoices on GSTN. But this fresh invoice will not have IRN
Know more about the e-invoice under GST
You can but in such case IRN will get removed from GSTR-1. Also you will first have to delete the invoice from GSTR-1 on which IRN was generated
Know more about einvoice under gst