multiple tax rate entries in an invoice

We can Prepare Single Bill

Its not mandatory

In One Bill We can Includes 5 % Tax rate Items , 10 % Tax Rate Items & other taxable items

There is no restriction. Kindly read section 32 of CGST Act and rule 49 of CGST Rules. You can prepare a single bill but you must clearly specify the taxable value, tax rate and tax amount for each slab.