An e-Invoice cannot be partially cancelled, it has to be cancelled fully. Once cancelled, it will need to be reported into the IRN within 24 hours. A cancellation done after 24 hours cannot be done on the IRN and needs to be manually cancelled on the GST portal before the returns are filed.
No E-invoice cannot be cancelled partially. E-invoice can be cancelled within 24 hrs , as data in IRP can be stored only upto 24 hrs & it cannot be cancelled once Eway has been generated for the same & as goods are in movement.
Note : Can be amended in GSTR 1 or Credit Note can be issued but for credit note also E-credit note need to be generated